What the heck is p-value?

Alice Matthews
3 min readNov 21, 2020

Journal club, teaching others about science and new innovations are some of the things I love. However, most of the peer-reviewed articles are very dense and many times even a small bit of help understanding them can go a long way. This week we are looking at p-value. p-value is important to understand when reading a scientific paper, as it is used a lot. When reading the graphs in a scientific paper it is helpful to understand the terminology.

So, what the heck is p-value?

The “p” stands for probability, so p-value is the probability value.

The p-value indicates how likely it is that a result occurred by chance alone.

The “p” stands for probability, so p-value is the probability value.

The p-value indicates how likely it is that a result occurred by chance alone.

If the p-value is small, it indicates the result was unlikely to have occurred by chance. These results are considered statically significant.

So, a small p-value indicates a greater than chance alone= SOMETHING HAPPENED; TEST IS SIGNIFICANT.

If the p-value is large, this indicates that the result is within “normal” or expected limits or it could indicate a sampling error.

So, a large p-value indicates= NOTHING HAPPENED; RESULT IS NOT SIGNIFICANT.

UNDERSTANDING ALPHA (a)

When interpreting whether a p-value is significant (beyond chance) or not, we need to know the alpha (a) being used for the experiment.

The two most common levels are:

a= .05 and a= .01

Alpha should be decided on by the researcher before beginning the experiment.

If a= .05 then the following rule applies:

If p < a then the result IS SIGNIFICANT

If p > a then the result IS NOT SIGNIFICANT

Here is an example:

Test result p= .03 given that a= .05

Because .03 < .05 this result is significant

If however, we run an experiment and the result returns a p= .12

Because .12 is greater than .05 this result is NOT significant, it is not beyond sampling error.

p-value Decision Outcome of Test

.040 p< .05 Significant

.075 p> .05 NOT significant

.049 p< .05 Significant

.523 p> .05 NOT significant

.001 p< .05 Significant

OK, but what if we decide that we want a higher degree of specificity?

We decide to use Alpha (a) = .01 as our p-value

If a = .01 then the following rules apply hint: it is the same as above

If p < a the result is significant. If p > a the result is NOT significant

Here we go

If we see p = .04 We know that Alpha (a) = .01 (that is what we choose before we began the experiment).

Therefore, if p = .04 > .01 this result IS NOT Significant

If our result returns such that our p = .003 and .003 is less than .01

Since p = .003 < .01 this result IS Significant

p-value Decision Outcome

.001 p < .01 Significant

.020 p > .01 NOT Significant

.009 p < .01 Significant

.523 p > .01 NOT Significant

.012 p > .01 Significant

Please, don’t even get me started on “p-hacking” and yes, it is a thing. Maybe, I will cover it in a new post. Science is hard, I’m here to help. Sometimes it is good to be little (like a small p-value).

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Alice Matthews

Graduate Student, Neuroscience, Medical Diagnostic Sonographer